SML1070

SR-58611A

≥98% (HPLC)

• 别名: Amibegron, [[(7S)-7-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydro-2-naphthalenyl]oxy acetic acid ethyl ester hydrochloride
• 经验公式（希尔记法）: C₂₂H₂₆ClNO₄ · HCl
• CAS号: 121524-09-2
• 分子量: 440.36
• MDL號碼: MFCD00886563
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825649
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]/D -75 to -95°, c = 0.5 in methanol
• 顏色: white to beige
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: −20°C
• SMILES 字串: ClC1=CC([C@@H](O)CN[C@@H]2CC(C=C(OCC(OCC)=O)C=C3)=C3CC2)=CC=C1.Cl
• InChI: 1S/C22H26ClNO4.ClH/c1-2-27-22(26)14-28-20-9-7-15-6-8-19(11-17(15)12-20)24-13-21(25)16-4-3-5-18(23)10-16;/h3-5,7,9-10,12,19,21,24-25H,2,6,8,11,13-14H2,1H3;1H/t19-,21-;/m0./s1
• InChI 密鑰: NQIZCDQCNYCVAS-RQBPZYBGSA-N
• 基因資訊: human ... ADRB3(155)

说明

生化／生理作用

SR58611A is a potent, specific 3β adrenergic receptor agonist.

SR58611A is a potent, specific b3 adrenergic receptor agonist. The EC₅₀ for reduction of β3-mediated spontaneous motility in rat distal colon sections is 3.5 nM. Minimal anti-depressant efficacious doses for SR58611A are 0.1-0.3 mpk in rodent models.

特點和優勢

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安全信息

• 象形圖: GHS09
• 訊號詞: Warning
• 危險聲明: H410
• 防範說明: P273 - P391 - P501
• 危險分類: Aquatic Acute 1 - Aquatic Chronic 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable