SML0617

A-804598

≥98% (HPLC)

• 别名: N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine
• 经验公式（希尔记法）: C₁₉H₁₇N₅
• CAS号: 1125758-85-1
• 分子量: 315.37
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 10 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: N(c2c3c(nccc3)ccc2)\C(=N/[C@@H](C)c1ccccc1)\NC#N
• InChI: 1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1
• InChI 密鑰: PQYCRDPLPKGSME-AWEZNQCLSA-N

说明

生化／生理作用

A-804598 is a P2X7 selective, competitive antagonist.

A-804598 is a P2X7 selective, competitive antagonist. In competition assays, the IC₅₀s for human, rat and mouse channels are 11, 10 and 9 nM, respectively.

特點和優勢

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P264 - P270 - P301 + P310 - P405 - P501
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable