SMB01026

Mosloflavon

≥90% (LC/MS-ELSD)

• 别名: 5-Hydroxy-6,7-dimethoxyflavone
• 经验公式（希尔记法）: C₁₇H₁₄O₅
• CAS号: 740-33-0
• 分子量: 298.29
• MDL號碼: MFCD00601540
• 分類程式碼代碼: 12352205
• NACRES: NA.25

属性

• 生物源: plant
• 化驗: ≥90% (LC/MS-ELSD)
• 形狀: solid
• 分子量: 298.29
• 溶解度: water: slightly soluble
• 應用: metabolomics; vitamins, nutraceuticals, and natural products
• 儲存溫度: −20°C
• InChI: 1S/C17H14O5/c1-20-14-9-13-15(16(19)17(14)21-2)11(18)8-12(22-13)10-6-4-3-5-7-10/h3-9,19H,1-2H3
• InChI 密鑰: SIVAITYPYQQYAP-UHFFFAOYSA-N

说明

一般說明

Mosloflavon, a 2-hydroxyflavanone, is a bioactive natural compound commonly derived from plants such as Mosla soochouensis, Desmos dumosus, Muntingia calabura, Cryptocarya chinensis, and Phonus arborescens. Extensive research indicates that this natural metabolite acts as an inhibitor may possess a wide range of biological activities, including anti-inflammatory, antioxidant, antiviral, antifungal, immunomodulatory, anti-infection, and anti-hypoxic properties.

應用

Mosloflavon is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

生化／生理作用

Mosloflavanone exhibits potent anti-EV71 activity by reducing visible cytopathic effects and suppressing virus replication during the initial infection phase. It also hinders the expression of the viral VP2 protein, thereby impeding viral capsid protein synthesis. Additionally, Mosloflavone demonstrates significant anti-inflammatory potential through the inhibition of TNF-α and IL-1β, with IC50 values of 16.4 μM and 6.4 μM, respectively. It shows a dose-dependent reduction in TNF-α, IL-1β, and iNOS levels in the supernatant of the mouse macrophage cell line J774A. This compound holds promise as a foundational element in the quest for treatments targeting inflammatory and immunomodulatory diseases.

特點和優勢

• Suitable for Biochemical and Biomedical research
• Versatile and adaptable for wide variety of laboratory and research applications

其他說明

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安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable