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Merck

SMB00370

Sigma-Aldrich

四氢姜黄素

≥96% (HPLC)

别名:

四氢姜黄素, 1,7-双(4-羟基-3-甲氧基苯基)-3,5-庚二酮, HZIV 81-2, NSC687845, 四氢呋喃基甲烷

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About This Item

经验公式(希尔记法):
C21H24O6
CAS号:
分子量:
372.41
Beilstein:
3485469
MDL號碼:
分類程式碼代碼:
12352205
PubChem物質ID:
NACRES:
NA.25

品質等級

化驗

≥96% (HPLC)

形狀

powder

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

−20°C

SMILES 字串

COc1cc(CCC(=O)CC(=O)CCc2ccc(O)c(OC)c2)ccc1O

InChI

1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3

InChI 密鑰

LBTVHXHERHESKG-UHFFFAOYSA-N

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一般說明

四氢姜黄素(THC)是姜黄素的无色代谢产物。结构与姜黄素类似。THC的化学结构中不含α, β-不饱和羰基。是来源于莪术(Curcuma zedoaria)、姜笋(Zingiber mioga)和姜(Zingiber officinale)根部的天然产物。

應用

四氢姜黄素(THC)已作为神经保护剂,研究其在缺血性中风小鼠模型中改善线粒体功能障碍的治疗潜力。

生化/生理作用

四氢姜黄素的治癌作用经过充分研究,具有出色的抗癌、抗血管生成和化学预防活性。还具有抗炎性。已发现四氢姜黄素可通过缓解氧化应激发挥针对糖尿病和血管功能障碍的抗氧化和保护作用。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

385.2 °F

閃點(°C)

196.2 °C


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Pooja Maharjan et al.
Archives of pharmacal research, 42(10), 909-925 (2019-04-29)
Ocular drug delivery has been a well-known route for the drug administration for the treatment of ocular diseases. However, numerous anatomical and physiological barriers prevailing in the eye itself create considerable challenges for achieving the necessitated therapeutic efficacy along with
Bharat B Aggarwal et al.
Molecules (Basel, Switzerland), 20(1), 185-205 (2014-12-31)
Curcumin (diferuloylmethane), a golden pigment from turmeric, has been linked with antioxidant, anti-inflammatory, anticancer, antiviral, antibacterial, and antidiabetic properties. Most of the these activities have been assigned to methoxy, hydroxyl, α,β-unsaturated carbonyl moiety or to diketone groups present in curcumin.
Nandan K Mondal et al.
Neurochemistry international, 122, 120-138 (2018-11-26)
The objectives of this study are to identify the mechanism of mitochondrial dysfunction during cerebral ischemic/reperfusion (I/R) injury and the therapeutic potential of tetrahydrocurcumin (THC) to mitigate mitochondrial dysfunction in experimental stroke model. In our study, 8-10 weeks old male

Global Trade Item Number

货号GTIN
SMB00370-1G4061826169797

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