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Merck
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Key Documents

SMB00251

Sigma-Aldrich

Avenacoside A

≥95% (LC/MS-ELSD)

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About This Item

经验公式(希尔记法):
C51H82O23
CAS号:
分子量:
1063.18
分類程式碼代碼:
12352200
NACRES:
NA.25

化驗

≥95% (LC/MS-ELSD)

形狀

solid

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

−20°C

InChI

1S/C51H82O23/c1-20-31-27(73-51(20)13-12-48(3,74-51)19-65-44-38(61)36(59)33(56)28(16-52)68-44)15-26-24-7-6-22-14-23(8-10-49(22,4)25(24)9-11-50(26,31)5)67-47-43(72-46-40(63)37(60)34(57)29(17-53)69-46)41(64)42(30(18-54)70-47)71-45-39(62)35(58)32(55)21(2)66-45/h6,20-21,23-47,52-64H,7-19H2,1-5H3/t20-,21-,23-,24+,25-,26-,27-,28+,29+,30+,31-,32-,33+,34+,35+,36-,37-,38+,39+,40+,41-,42+,43+,44+,45-,46-,47+,48-,49-,50-,51-/m0/s1

InChI 密鑰

AAJHVVLGKCKBSH-QTPGKRPGSA-N

一般說明

Avenacoside A is a natural product derived from a plant source and exclusively present in whole grain oat. Avenacoside A is glycosylated with a trisaccharide at C-3 and with a glucose unit at C-26 position.

應用

Avenacoside A may have been used as a reference standard to identify the metabolite annotation in the leaves of various Avena sativa (oats) cultivars.

生化/生理作用

Avenacoside A displays anti-proliferative effects by inhibiting the growth of human colon cancer cells.It also serves as an exposure biomarker that is considered for epidemiologic studies with respect to whole grain uptake.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Avenacosides: Metabolism, and potential use as exposure biomarkers of oat intake
Wang P, et al.
Molecular Nutrition And Food Research, 61(7), 1700196-1700196 (2017)
Myoungjae Kim et al.
Molecules (Basel, Switzerland), 24(21) (2019-10-28)
Pancreatic cancer (PC) is one of the most aggressive malignancies in the world. Gemcitabine (Gem), a nucleoside pyrimidine analogue, is a first-line chemotherapeutic drug for PC, but the tumor response rate of Gem is very low and resistance to Gem
Chanel J Pretorius et al.
Metabolites, 11(3) (2021-04-04)
The first step in crop introduction-or breeding programmes-requires cultivar identification and characterisation. Rapid identification methods would therefore greatly improve registration, breeding, seed, trade and inspection processes. Metabolomics has proven to be indispensable in interrogating cellular biochemistry and phenotyping. Furthermore, metabolic

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