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化驗
≥95% (LC/MS-ELSD)
形狀
solid
應用
metabolomics
vitamins, nutraceuticals, and natural products
儲存溫度
−20°C
SMILES 字串
C[N+](C)(C)C(Cc1c[nH]c2ccccc12)C([O-])=O
InChI
1S/C14H18N2O2/c1-16(2,3)13(14(17)18)8-10-9-15-12-7-5-4-6-11(10)12/h4-7,9,13,15H,8H2,1-3H3
InChI 密鑰
AOHCBEAZXHZMOR-UHFFFAOYSA-N
一般說明
Hypaphorine is a natural product derived from a plant source. It is an indolic compound, initially isolated from Pisolithus tinctorius, an ectomycorrhizal fungus. This compound is made up of tryptophan and three methyl groups. It is recently identified as one of the components of human milk. Hypaphorinecan also be sourced from marine organisms.
生化／生理作用
Hypaphorine has demostrated sleep promoting properties by increasing non-rapid eye movement sleep duration for the first hour after it is administered in mice.
Hypaphorine is known to reduce glucose levels in rat models. Along with this, it possesses anti-inflammatory and certain neurological functions.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Hypaphorine, an indole alkaloid from Erythrina velutina, induced sleep on normal mice
Ozawa M, et al.
Bioorganic & Medicinal Chemistry Letters, 18(14) (2008)
Hypaphorine is present in human milk in association with consumption of legumes
Keller BO, et al.
Journal of Agricultural and Food Chemistry, 61(31) (2013)
Competitive antagonism between IAA and indole alkaloid hypaphorine must contribute to regulate ontogenesis
Jambois A, et al.
Physiologia Plantarum, 123(2) (2005)
Hypaphorine attenuates lipopolysaccharide-induced endothelial inflammation via regulation of TLR4 and PPAR-g dependent on PI3K/Akt/mTOR signal pathway
Sun H, et al.
International Journal of Molecular Sciences, 18(4), 844-844 (2017)
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