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Merck
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Key Documents

SCP0003

Sigma-Aldrich

Proteasome Substrate 1, fluorogenic

≥95% (HPLC), lyophilized

别名:

Z-LLL-AMC, Z-Leu-Leu-Leu-AMC

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About This Item

经验公式(希尔记法):
C36H48N4O7
分子量:
648.79
分類程式碼代碼:
12352200
NACRES:
NA.32

product name

Proteasome Substrate 1, fluorogenic,

化驗

≥95% (HPLC)

形狀

lyophilized

成份

Peptide Content, ≥80%

儲存條件

protect from light

儲存溫度

−20°C

Amino Acid Sequence

Z-Leu-Leu-Leu-AMC

生化/生理作用

Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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S Tsubuki et al.
Biochemical and biophysical research communications, 196(3), 1195-1201 (1993-11-15)
A tripeptide aldehyde protease inhibitor, benzyloxycarbonyl(Z)-Leu-Leu-leucinal (ZLLLa1), initiates neurite outgrowth in PC12 cells at an optimal concentration of 30nM. This result suggests the existence of a protease which regulates neurite formation in PC12 cells. We report here an attempt to
Oriane Tasta et al.
Free radical biology & medicine, 164, 303-314 (2021-01-16)
Premature placental senescence is a hallmark of pregnancy-related disorders such as intrauterine growth restriction (IUGR) and preeclampsia (PE), two major cause of maternal and neonatal morbidity and mortality. Oxidative stress and lipid peroxidation are involved in the pathogenesis of PE

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