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Merck
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Key Documents

SAB5702865

Sigma-Aldrich

Anti-EGFR (L858R) Antibody, clone 1J5C6, Rabbit Monoclonal

别名:

ERBB, ERBB1, HER1, NISBD2, PIG61, mENA

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About This Item

分類程式碼代碼:
12352203

生物源

rabbit

品質等級

材料

colorless

無性繁殖

1J5C6, monoclonal

形狀

liquid

分子量

175 kDa

物種活性

mouse, mouse

濃度

1.30 mg/mL

技術

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

DYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... EGFR(1956)

一般說明

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 800-900 of human EGFR (L858R) (P00533).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IHC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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