生物源
rabbit
品質等級
材料
colorless
無性繁殖
5Y8J0, monoclonal
形狀
liquid
分子量
17-250 kDa
物種活性
rat, rat, human
濃度
2 mg/mL
技術
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000
顏色
colorless
一般說明
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Ubiquitin (P0CG47).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
應用
WB, IF/ICC
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
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