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Merck
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主要文件

SAB5702418

Sigma-Aldrich

Anti-Ubiquitin Antibody, clone 5Y8J0, Rabbit Monoclonal

别名:

HEL-S-50

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

价格与库存信息目前不能提供

生物源

rabbit

品質等級

材料

colorless

無性繁殖

5Y8J0, monoclonal

形狀

liquid

分子量

17-250 kDa

物種活性

rat, rat, human

濃度

2 mg/mL

技術

immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000

顏色

colorless

一般說明

This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Ubiquitin (P0CG47).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IF/ICC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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