SAB5702282

Anti-SOCS1 Antibody, clone 5T6Z10, Rabbit Monoclonal

• 别名: SOCS1,CIS1,CISH1,JAB,SOCS-1,SSI-1,SSI1,TIP3,TIP-3
• 分類程式碼代碼: 12352203
• NACRES: NA.46

属性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 5T6Z10, monoclonal
• 形狀: liquid
• 物種活性: rat, human, rat
• 濃度: 1 mg/mL
• 技術: immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200
• 顏色: colorless
• 同型: IgG
• 免疫原序列: MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGT
• UniProt登錄號: O15524
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SOCS1(8651)

说明

一般說明

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SOCS1 (NP_003736.1).

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

應用

IHC, IF/ICC

安全信息

• 象形圖: GHS07,GHS09
• 訊號詞: Warning
• 危險聲明: H317,H411
• 防範說明: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• 危險分類: Aquatic Chronic 2 - Skin Sens. 1
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3