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Merck
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Key Documents

SAB5702178

Sigma-Aldrich

Anti-Thyroid Peroxidase Antibody, clone 3C4A4, Rabbit Monoclonal

别名:

MSA, TDH2A, TPX

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

材料

colorless

無性繁殖

3C4A4, monoclonal

形狀

liquid

物種活性

rat, human, rat

濃度

1.09 mg/mL

技術

immunohistochemistry: 1:50 - 1:200

顏色

colorless

同型

IgG

免疫原序列

MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQA

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... TPO(7173)

一般說明

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thyroid Peroxidase (P07202).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

IHC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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