SAB5702162

Anti-Serotonin transporter Antibody, clone 5T7M2, Rabbit Monoclonal

• 别名: 5-HTT,5-HTTLPR,5HTT,HTT,OCD1,SERT,SERT1,hSERT,SLC6A4
• 分類程式碼代碼: 12352203
• NACRES: NA.46

属性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 5T7M2, monoclonal
• 形狀: liquid
• 分子量: 70 kDa
• 物種活性: human, rat
• 濃度: 0.25 mg/mL
• 技術: immunofluorescence: 1:50 - 1:200; western blot: 1:500 - 1:1000
• 顏色: colorless
• 同型: IgG
• 免疫原序列: METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLG
• UniProt登錄號: P31645
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SLC6A4(6532)

说明

一般說明

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Serotonin transporter (P31645).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IF/ICC

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1