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Merck
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Key Documents

SAB5701767

Sigma-Aldrich

Anti-Phospho-α-Synuclein-S129 antibody produced in rabbit

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.43

生物源

rabbit

品質等級

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

liquid

物種活性

human

濃度

1.35 mg/mL

技術

western blot: 1:500-1:1000

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

phosphorylation (pSer129 )

基因資訊

human ... SNCA(6622)

一般說明

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer′s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

免疫原

A phospho specific peptide corresponding to residues surrounding S129 of human alpha-Synuclein

外觀

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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