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Merck
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Key Documents

SAB5700686

Sigma-Aldrich

Anti-DDIT3/CHOP antibody produced in rabbit

别名:

C/EBPzeta, CEBPZ, CHOP, CHOP-10, CHOP10, DDIT3, DDIT3 / CHOP, GADD153

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

19
21

物種活性

mouse, rat, human

濃度

2.38 mg/ml

技術

immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... DDIT3(1649)

一般說明

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-169 of human DDIT3 / CHOP (NP_004074.2).

外觀

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

儲存和穩定性

Store at -20℃. Avoid freeze / thaw cycles.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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