推荐产品
生物源
rabbit
品質等級
重組細胞
expressed in proprietary host
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
SP188, monoclonal
物種活性
human (tested)
技術
flow cytometry: 1:400
immunoblotting: 1:400
immunohistochemistry: 1:100
同型
IgG
UniProt登錄號
運輸包裝
wet ice
儲存溫度
2-8°C
目標翻譯後修改
unmodified
基因資訊
human ... MAGEA1(4100)
一般說明
Melanoma-associated antigen 1 (MAGE-A1) is a member of the MAGE family. It is encoded by the gene mapped to human chromosome Xq28.
Melanoma-associated antigen 1 (MAGE-A1) is one of the melanoma associated antigens (MAAs). MAGE-A1 is highly expressed in testis and some human solid tumors such as melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian and renal cell carcinomas.
免疫原
Synthetic peptide derived from the C-terminus of human MAGE-A1 protein.
生化/生理作用
Members of MAGE family play a vital role in maintaining normal cellular physiology. Melanoma-associated antigen 1 (MAGE-A1) serves as a target antigen of patient-derived CD8+ T cells in melanoma. It might be potential target for treating melanoma patients.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
MAGE-A1 promotes melanoma proliferation and migration through C-JUN activation.
Biochemical and Biophysical Research Communications, 473(4), 959-965 (2016)
MAGE-F1, a novel ubiquitously expressed member of the MAGE superfamily.
Gene, 267(2), 173-182 (2001)
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