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Merck
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Key Documents

SAB5500139

Sigma-Aldrich

Anti-MAGE-A1 antibody, Rabbit monoclonal

clone SP188, recombinant, expressed in proprietary host, affinity isolated antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

重組細胞

expressed in proprietary host

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

SP188, monoclonal

物種活性

human (tested)

技術

flow cytometry: 1:400
immunoblotting: 1:400
immunohistochemistry: 1:100

同型

IgG

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... MAGEA1(4100)

一般說明

Melanoma-associated antigen 1 (MAGE-A1) is a member of the MAGE family. It is encoded by the gene mapped to human chromosome Xq28.
Melanoma-associated antigen 1 (MAGE-A1) is one of the melanoma associated antigens (MAAs). MAGE-A1 is highly expressed in testis and some human solid tumors such as melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian and renal cell carcinomas.

免疫原

Synthetic peptide derived from the C-terminus of human MAGE-A1 protein.

生化/生理作用

Members of MAGE family play a vital role in maintaining normal cellular physiology. Melanoma-associated antigen 1 (MAGE-A1) serves as a target antigen of patient-derived CD8+ T cells in melanoma. It might be potential target for treating melanoma patients.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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访问文档库

MAGE-A1 promotes melanoma proliferation and migration through C-JUN activation.
Wang D, et al.
Biochemical and Biophysical Research Communications, 473(4), 959-965 (2016)
MAGE-F1, a novel ubiquitously expressed member of the MAGE superfamily.
Stone B, et al.
Gene, 267(2), 173-182 (2001)

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