推荐产品
生物源
rabbit
品質等級
重組細胞
expressed in proprietary host
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
SP228, monoclonal
物種活性
human (tested)
技術
flow cytometry: 1:100
immunohistochemistry: 1:100
同型
IgG
UniProt登錄號
運輸包裝
wet ice
儲存溫度
2-8°C
目標翻譯後修改
unmodified
基因資訊
human ... HLA-DPA1(3113)
相关类别
一般說明
HLA-DP is an antigen receptor and one of the MHC class II proteins. HLA-DP is a heterodimer of an alpha and a beta chain. Both chains are type I transmembrane proteins with short cytoplasmic domains. It is expressed on antigen-presenting cells and a variety of other cell types, and is also expressed by various tumors such as melanoma, gastric carcinoma, breast carcinoma, ovarian carcinoma, and lymphoma.
Major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1) is a class II heterodimer comprising of a polymorphic β and an oligomorphic α chain. It is encoded by the gene mapped to human chromosome 6p21.33. HLA-DPA1 is generally expressed on a subset of Kupffer cells and resident macrophages in liver.
免疫原
Synthetic peptide derived from human HLA-DP alpha1 protein.
應用
Anti-HLA-DP alpha 1 antibody, Rabbit monoclonal has been used in immunohistochemistry.
生化／生理作用
Major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1) alloreactivity is highly relevant in clinical transplantation. It plays an essential role in the presentation of viral antigens to CD4+ T helper (Th) lymphocytes. Studies have suggested that SNP (single nucleotide polymorphisms) of HLA-DP can result in chronic hepatitis B virus (HBV) infection.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
HLA-DP Polymorphisms Affect the Outcomes of Chronic Hepatitis B Virus Infections, Possibly through Interacting with Viral Mutations
Zhang Q, et al.
Journal of Virology, 02073-02073 (2013)
Allorecognition of HLA-DP by CD4+ T cells is affected by polymorphism in its alpha chain.
Lauterbach N, et al.
Molecular Immunology, 59(1), 19-29 (2014)
New loci associated with chronic hepatitis B virus infection in Han Chinese.
Hu Z, et al.
Nature Genetics, 45(12), 1499-1499 (2013)
Studies on the association of single nucleotide polymorphisms of HLA-DP and DQ genes with the outcome of chronic hepatitis B virus infection
Su M, et al.
Zhonghua yi xue yi chuan xue za zhi (Chinese Journal of Medical Genetics), 31(6), 765-769 (2014)
Pulsed electrical stimulation benefits wound healing by activating skin fibroblasts through the TGF?1/ERK/NF-?B axis.
Wang Y, et al.
Biochimica et Biophysica Acta, 1860(7), 1551-1559 (2016)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门