SAB4702062

Monoclonal Anti-HLA-E purified produced in mouse

• 别名: HLA class I histocompatibility antigen, MHC class I antigen E, alpha chain E
• 分類程式碼代碼: 12352203

属性

• 共軛: unconjugated
• 品質等級: 100
• 抗體產品種類: primary antibodies
• 無性繁殖: MEM-E/02, monoclonal
• 形狀: buffered aqueous solution
• 物種活性: ( Non-human primates), human
• 濃度: 1 mg/ml
• 技術: immunohistochemistry: suitable; western blot: suitable
• 同型: IgG1
• UniProt登錄號: P13747
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... HLA-E(3133)

说明

一般說明

HLA-E (human leukocyte antigen E) is a non-classical MHC I antigen, which is important for dialogue with NK cells and their regulation through interaction with CD94/NKG2 receptor. Like other MHC I molecules, transmembrane HLA-E molecule (45 kDa) associates with beta2 microglobulin. Unlike HLA-G, expression of HLA-E molecules is not so restricted, but it has been detected at least at mRNA level in virtually all cells and tissues examined. In peripheral blood, HLA-E protein is expressed at least in all mononuclear cells, but in different quantity (B cells and monocytes more than T cells and NK cells).

特異性

The antibody MEM-E/02 specifically reacts with an extracellular epitope on denaturated heavy chain of human HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of all human cell types.

免疫原

Recombinant human HLA-E denaturated heavy chain.

外觀

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

準備報告

Purified by protein-A affinity chromatography.

儲存和穩定性

Store at 2-8°C. Do not freeze.

其他說明

The antibody solution should be gently mixed before use.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable