跳转至内容
Merck
所有图片(5)

Key Documents

SAB4504269

Sigma-Aldrich

Anti-phospho-TGF β Receptor II (pSer225/250) antibody produced in rabbit

affinity isolated antibody

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352203
NACRES:
NA.43

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 64 kDa

物種活性

mouse, rat, human

濃度

~1 mg/mL

技術

ELISA: 1:10000
immunohistochemistry: 1:50-1:100

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

phosphorylation (pSer225/pSer250)

基因資訊

human ... TGFBR2(7048)

一般說明

Transforming growth factor β receptor 2 (TGFBR2) is a serine/threonine protein kinase, that belongs to the TGFβ receptor subfamily. It is located on human chromosome 3p24.

免疫原

The antiserum was produced against synthesized peptide derived from human TGF beta Receptor II around the phosphorylation site of Ser225/250.

Immunogen Range: 191-240

生化/生理作用

Transforming growth factor β receptor 2 (TGFBR2) plays an important role in signal transduction resulting in mitogenic responses. Mutation in TGFBR2 result in Loeys-Dietz syndrome and Marfan syndrome.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到合适的产品?  

试试我们的产品选型工具.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Arthrogryposis as neonatal presentation of Loeys-Dietz syndrome due to a novel TGFBR2 mutation
Valenzuela I, et al.
European Journal of Medical Genetics, 60(6), 303-307 (2017)
Heterozygous TGFBR2 mutations in Marfan syndrome
Mizuguchi T, et al.
Nature Genetics, 36(8), 855-860 (2004)
TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficient HCT116 colorectal cancer cells
Fricke F, et al.
Cell communication and signaling : CCS, 15, 14-14 (2017)
Molecular modeling and molecular dynamic simulation of the effects of variants in the TGFBR2 kinase domain as a paradigm for interpretation of variants obtained by next generation sequencing
Zimmermann MT, et al.
PLoS ONE, 12(2), e0170822-e0170822 (2017)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门