推荐产品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 31 kDa
物種活性
mouse, rat, human
濃度
~1 mg/mL
技術
ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
phosphorylation (pSer150)
基因資訊
human ... CASP3(836)
一般說明
Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3 is an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases. CASP3 is mapped to human chromosome 4q35.1.
免疫原
The antiserum was produced against synthesized peptide derived from human Caspase 3 around the phosphorylation site of Ser150.
Immunogen Range: 116-165
Immunogen Range: 116-165
生化／生理作用
Caspase-3 (CASP3) can degenerate multiple cellular proteins and results in morphological changes and DNA fragmentation in cells at the time of apoptosis. It participates in the growth stimulation. CASP3 plays a major role in the execution phase of apoptosis.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma.
Liu PF, et al.
PLoS ONE, 12(7), e0180620-e0180620 (2017)
Caspase 3?mediated stimulation of tumor cell repopulation during cancer radiotherapy.
Huang Q, et al.
Nature Medicine, 17(7), 860?866-860?866 (2011)
CASP3 gene single-nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children.
Kuo HC, et al.
Journal of Human Genetics, 56(2), 161?165-161?165 (2011)
Identification of SMURF1 as a possible target for 7q21. 3?22.1 amplification detected in a pancreatic cancer cell line by in?house array?based comparative genomic hybridization.
Suzuki A, et al.
Cancer Science, 99(5), 986-994 (2008)
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