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生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 72 kDa
物種活性
human, mouse, rat
濃度
~1 mg/mL
技術
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
phosphorylation (pTyr348)
基因資訊
human ... SYK(6850)
一般說明
Spleen tyrosine kinase (SYK) is a member of the non-receptor tyrosine kinase family. It is usually expressed in epithelial breast tissues and hematopoietic cells.SYK is mapped to human chromosome 9q22.
免疫原
The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr348.
Immunogen Range: 314-363
Immunogen Range: 314-363
生化／生理作用
Spleen tyrosine kinase (SYK), as a tumor suppressor gene helps to prevent the development and metastasis of breast cancer cells.It participates in B-cell receptor signaling.This protein helps to phosphorylate the α-tubulin subunits of microtubules.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Syk: a new player in the field of breast cancer
Stewart ZA and Pietenpol JA
Breast Cancer Research, 3(1), 5-7 (2001)
Novel SYK gene variations and changes in binding sites of miRs in breast cancer patients
Faryal R, et al.
Cancer Biomarkers : Section A of Disease Markers, 16(3), 319-326 (2016)
Genomic and expression profiling identifies the B-cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma
Rinaldi A, et al.
British Journal of Haematology, 132(3), 303-316 (2006)
Jiancheng Hu et al.
Journal of immunology (Baltimore, Md. : 1950), 193(1), 85-95 (2014-06-04)
Lysophospholipids have emerged as biologically important chemoattractants capable of directing lymphocyte development, trafficking, and localization. Lysophosphatidic acid (LPA) is a major lysophospholipid found systemically, and its levels are elevated in certain pathological settings, such as cancer and infections. In this
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