SAB4503821

Anti-phospho-HSL (pSer^855/554) antibody produced in rabbit

affinity isolated antibody

• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 116 kDa
• 物種活性: mouse, rat, human
• 濃度: ~1 mg/mL
• 技術: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI登錄號: Q05469
• UniProt登錄號: Q05469
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pSer855/pSer554)
• 基因資訊: human ... LIPE(3991)

说明

一般說明

Hormone sensitive lipase (HSL) is coded by LIPE (lipase E) gene. The gene coding for a protein is mapped on human chromosome 19q13. The encoded protein is an intracellular lipase with various neutral lipid substrates, such as triglycerides, diglycerides, monoglycerides, cholesterol esters and retinyl esters. HSL is widely expressed.

免疫原

The antiserum was produced against synthesized peptide derived from human HSL around the phosphorylation site of Ser855/554.

Immunogen Range: 520-569

生化／生理作用

Hormone sensitive lipase (HSL) plays an important role in various processes such as lipolysis, adipocytes, steroidogenesis and spermatogenesis. Deficiency of HSL contributes to histologic abnormalities in white adipose tissue and an increase in macrophage infiltration. Polymorphism in the gene has been observed in familial lipodystrophies patients.

特點和優勢

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外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable