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生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 23 kDa
物種活性
human
濃度
~1 mg/mL
技術
ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... FGF18(8817)
一般說明
Anti-FGF18 Antibody detects endogenous levels of total FGF18 protein.
FGF18 (fibroblast growth factor 18) is a member of the paracrine-acting FGF8 subfamily. It is expressed in the perichondrium and joints of developing long bones. FGF18 is a 21.2 kDa glycosylated secretory protein, that is structurally similar to FGF8 and FGF17. It is mapped to human chromosome 5q35.1. Anti-FGF18 Antibody detects endogenous levels of total FGF18 protein.
FGF18 (fibroblast growth factor 18) is a member of the paracrine-acting FGF8 subfamily. It is expressed in the perichondrium and joints of developing long bones. FGF18 is a 21.2 kDa glycosylated secretory protein, that is structurally similar to FGF8 and FGF17. It is mapped to human chromosome 5q35.1. Anti-FGF18 Antibody detects endogenous levels of total FGF18 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human FGF18.
Immunogen Range: 151-200
Immunogen Range: 151-200
生化／生理作用
FGF18 (fibroblast growth factor 18) plays an important role in the skeletal development of the embryonic and adult organism. It is associated with colorectal and ovarian cancer. FGF18 participates in cell proliferation and differentiation during osteogenesis and chondrogenesis. It is essential for the growth of bone, cartilage, hair, cardiovasculature and alveolus.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis.
Ohbayashi N, et al.
Genes & Development, 16(7), 870-879 (2002)
The crystal structure of fibroblast growth factor 18 (FGF18).
Alan B, et al.
Protein & cell, 5(5), 343?347-343?347 (2014)
Wei Wei et al.
The Journal of clinical investigation, 123(10), 4435-4448 (2013-09-11)
High-throughput genomic technologies have identified biomarkers and potential therapeutic targets for ovarian cancer. Comprehensive functional validation studies of the biological and clinical implications of these biomarkers are needed to advance them toward clinical use. Amplification of chromosomal region 5q31-5q35.3 has
Nobuyuki Itoh et al.
Trends in genetics : TIG, 20(11), 563-569 (2004-10-12)
Fibroblast growth factors (Fgfs) and Fgf receptors (Fgfrs) comprise a signaling system that is conserved throughout metazoan evolution. Twenty-two Fgfs and four Fgfrs have been identified in humans and mice. During evolution, the Fgf family appears to have expanded in
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