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Merck
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主要文件

SAB4503399

Sigma-Aldrich

Anti-LAT3 antibody produced in rabbit

affinity isolated antibody

别名:

L-type amino acid transporter 3, Prostate cancer overexpressed gene 1 protein, SLC43A1, Solute carrier family 43 member 1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
共軛:
unconjugated
application:
ELISA
WB
無性繁殖:
polyclonal
物種活性:
human
citations:
3
技術:
ELISA: 1:20000
western blot: 1:500-1:1000

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 61 kDa

物種活性

human

濃度

~1 mg/mL

技術

ELISA: 1:20000
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... SLC43A1(8501)

相关类别

一般說明

Anti-LAT3 Antibody detects endogenous levels of total LAT3 protein.
LAT3/SLC43A1 (solute carrier family 43 member 1), a Na+-independent neutral L-amino acid transporter, is mapped to human chromosome 11q12.1. It is expressed in liver, skeletal muscle and pancreas.

免疫原

The antiserum was produced against synthesized peptide derived from human LAT3.

Immunogen Range: 231-280

生化/生理作用

LAT3/SLC43A1 (solute carrier family 43 member 1) is essential for the growth and activities of podocytes. In prostate cancer cell lines, silencing the expression of LAT3 stops the initiation of mTORC1 (mammalian target of rapamycin complex 1) pathway activation, cell growth and cell cycle both in vitro and in vivo.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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访问文档库

Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth
Wang Q, et al.
ACS Chemical Biology, 9(6), 1369-1376 (2014)
Amino acid transporter LAT3 is required for podocyte development and function
Sekine Y, et al.
Journal of the American Society of Nephrology, 20(7), 1586-1596 (2009)
Genome-wide analysis of pancreatic cancer using microarray-based techniques.
Harada T
Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.], 9(1-2), 13-24 (2009)

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