生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 61 kDa
物種活性
human
濃度
~1 mg/mL
技術
ELISA: 1:20000
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... SLC43A1(8501)
一般說明
Anti-LAT3 Antibody detects endogenous levels of total LAT3 protein.
LAT3/SLC43A1 (solute carrier family 43 member 1), a Na+-independent neutral L-amino acid transporter, is mapped to human chromosome 11q12.1. It is expressed in liver, skeletal muscle and pancreas.
免疫原
The antiserum was produced against synthesized peptide derived from human LAT3.
Immunogen Range: 231-280
Immunogen Range: 231-280
生化/生理作用
LAT3/SLC43A1 (solute carrier family 43 member 1) is essential for the growth and activities of podocytes. In prostate cancer cell lines, silencing the expression of LAT3 stops the initiation of mTORC1 (mammalian target of rapamycin complex 1) pathway activation, cell growth and cell cycle both in vitro and in vivo.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth
ACS Chemical Biology, 9(6), 1369-1376 (2014)
Amino acid transporter LAT3 is required for podocyte development and function
Journal of the American Society of Nephrology, 20(7), 1586-1596 (2009)
Genome-wide analysis of pancreatic cancer using microarray-based techniques.
Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.], 9(1-2), 13-24 (2009)
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