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一般說明
Anti-TBP antibody detects endogenous levels of total TBP protein.
The TBP (TATA-binding protein) gene is mapped to human chromosome 6q27.
免疫原
The antiserum was produced against synthesized peptide derived from human TBP.
Immunogen Range: 151-200
Immunogen Range: 151-200
生化／生理作用
The TBP (TATA-binding protein) gene encodes a subunit of TFIIIB (transcription factor IIIB) complex and recognizes the TATA box in the DNA. It thus, plays an important role in RNA polymerase II transcription machinery. TBP is known to induce stress granule formation in hepatitis B viral infection.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Taspase1 processing alters TFIIA cofactor properties in the regulation of TFIID.
Malecova B
Transcription, 6(2), 21-32 (2015)
The Pathogenic Role of Low Range Repeats in SCA17.
Shin JH
PLoS ONE, 10(8), 1-10 (2015)
Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation.
Gouge J
Nature Communications, 8(1):130, 1-11 (2017)
Doubly Spliced RNA of Hepatitis B Virus Suppresses Viral Transcription via TATA-Binding Protein and Induces Stress Granule Assembly.
Tsai KN
Journal of Virology, 89(22), 11406-11419 (2015)
Francisco J Herrera et al.
eLife, 3, e02559-e02559 (2014-07-10)
Emerging evidence points to an unexpected diversification of core promoter recognition complexes that serve as important regulators of cell-type specific gene transcription. Here, we report that the orphan TBP-associated factor TAF9B is selectively up-regulated upon in vitro motor neuron differentiation
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