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生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 49 kDa
物種活性
mouse, rat, human
濃度
~1 mg/mL
技術
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... KRT15(3866)
一般說明
Anti-Keratin 15 Antibody detects endogenous levels of total Keratin 15 protein.
Keratin 15 (KRT15)/cytokeratin 15, a type I keratin, belongs to the keratin (KRT) gene family. It is expressed in basal keratinocytes of stratified epithelium. KRT15 gene is located on human chromosome 17q21.2. Anti-Keratin 15 antibody detects endogenous levels of total Keratin 15 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human Keratin 15.
Immunogen Range: 1-50
Immunogen Range: 1-50
應用
Anti-Keratin 15 antibody produced in rabbit has been used in: immunohistochemistry (1:100), immunofluorescence (1:100), immunostaining
生化／生理作用
Keratin 15 (KRT15) participates in maintaining cytoplasmic stability. It acts as a marker for skin stem cells in the hair follicle bulge. KRT15 plays a major role in epidermal homeostasis. It is associated with tumorigenesis. KRT15 might serve as a biomarker in predicting the prognosis of breast invasive carcinoma (BRCA) patients. Overexpression of the KRT15 gene is seen in squamous-cell carcinoma.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Development of the human prostate
Cunha GR, et al.
Differentiation, 103, 24-45 (2018)
X Rao et al.
Neoplasma, 67(2), 410-414 (2019-12-31)
Keratin-15 (KRT15) is a type I keratin lacking a defined type II partner and plays a key role in maintaining cytoplasmic stability. Recently, studies have reported that KRT15 was correlated with tumor formation and progression. However, the clinical significance of
Pengcheng Zhong et al.
Experimental and therapeutic medicine, 21(4), 305-305 (2021-03-16)
Although keratin 15 (KRT15) has been indicated to be overexpressed in several types of tumor, its role in breast invasive carcinoma (BRCA) has so far remained elusive. The aim of the present study was to explore KRT15 expression in BRCA
Gerald R Cunha et al.
Differentiation; research in biological diversity, 103, 24-45 (2018-09-19)
This paper provides a detailed compilation of human prostatic development that includes human fetal prostatic gross anatomy, histology, and ontogeny of selected epithelial and mesenchymal differentiation markers and signaling molecules throughout the stages of human prostatic development: (a) pre-bud urogenital
Gerald R Cunha et al.
Differentiation; research in biological diversity, 115, 37-52 (2020-08-30)
The goal of this paper is to explore the ability of the human female urogenital sinus immediately below the bladder (proximal urethra) to undergo prostatic development in response to dihydrotestosterone (DHT). To establish this idea, xenografts of human fetal female
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