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Key Documents

SAB4501583

Sigma-Aldrich

Anti-Integrin β1 antibody produced in rabbit

affinity isolated antibody

别名:

CD29, FNRB, Fibronectin receptor β subunit, ITB1, Integrin VLA-4 β subunit

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 88 kDa

物種活性

human, rat, mouse

濃度

~1 mg/mL

技術

ELISA: 1:1000
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... ITGB1(3688)

一般說明

Anti-Integrin β1 Antibody detects endogenous levels of total Integrin β1 protein.
Integrin β1 is a mechanosensor, that is located on human chromosome 10p11.22. It is present in normal cells and tumor-associated cells.

免疫原

The antiserum was produced against synthesized peptide derived from human Integrin beta1.

Immunogen Range: 746-795

應用

Anti-Integrin β1 antibody has been used in western blotting.

生化/生理作用

Integrin β1 acts as an adhesive molecule in the development of de novo focal contact, keratinocyte migration and re-epithelialization of wound tissue.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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β1 Integrin as a Prognostic and Predictive Marker in Triple-Negative Breast Cancer.
Yin HL, et al.
International Journal of Molecular Sciences, 17(9) (2016)
Ggnbp2-Null Mutation in Mice Leads to Male Infertility due to a Defect at the Spermiogenesis Stage.
Liu L,et al.
The American Journal of Pathology, 187(11), 2508-2519 (2017)
Genomic aberrations associated with erlotinib resistance in non-small cell lung cancer cells.
Serizawa M, et al.
Anticancer Research, 33(12), 5223-5233 (2013)
β1 integrin signaling in asymmetric migration of keratinocytes under mechanical stretch in a co-cultured wound repair model.
Lu D, et al.
BioMedical Engineering OnLine, 15(2), 130-130 (2016)
Lingyun Liu et al.
The American journal of pathology, 187(11), 2508-2519 (2017-08-22)
Gametogenetin binding protein 2 (GGNBP2) is an evolutionarily conserved zinc finger protein. Although Ggnbp2-null embryos in the B6 background died because of a defective placenta, 6.8% of Ggnbp2-null mice in the B6/129 mixed background were viable and continued to adulthood.

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