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Merck
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Key Documents

SAB4501568

Sigma-Aldrich

Anti-IRS-1 antibody produced in rabbit

affinity isolated antibody

别名:

IRS-1, IRS1, Insulin receptor substrate-1

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About This Item

MDL號碼:
MFCD01633547
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 131 kDa

物種活性

human, mouse, rat

濃度

~1 mg/mL

技術

ELISA: 1:1000
immunohistochemistry: 1:50-1:100

NCBI登錄號

P35568

UniProt登錄號

P35568

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... IRS1(3667)

一般說明

Anti-IRS-1 Antibody detects endogenous levels of total IRS-1 protein.

免疫原

The antiserum was produced against synthesized peptide derived from human IRS-1.

Immunogen Range: 578-627

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

nwg

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Huai-Chia Chuang et al.
Nature communications, 5, 4602-4602 (2014-08-08)
Proinflammatory cytokines play important roles in insulin resistance. Here we report that mice with a T-cell-specific conditional knockout of HGK (T-HGK cKO) develop systemic inflammation and insulin resistance. This condition is ameliorated by either IL-6 or IL-17 neutralization. HGK directly
Rahul Agrawal et al.
Biochimica et biophysica acta, 1842(9), 1313-1323 (2014-05-21)
The rising prevalence of type-2 diabetes is becoming a pressing issue based on emerging reports that T2DM can also adversely impact mental health. We have utilized the UCD-T2DM rat model in which the onset of T2DM develops spontaneously across time
Águeda González-Rodríguez et al.
Disease models & mechanisms, 7(9), 1093-1100 (2014-07-06)
Oxidative stress contributes to the progression of acute liver failure (ALF). Transcription factor nuclear factor-erythroid 2-related factor (Nrf2) serves as an endogenous regulator by which cells combat oxidative stress. We have investigated liver damage and the balance between death and

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