推荐产品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 18 kDa
物種活性
mouse, human, rat
濃度
~1 mg/mL
技術
ELISA: 1:40000
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... CFL2(1073)
一般說明
Anti-Cofilin Antibody detects endogenous levels of total Cofilin protein.
Cofilin is a member of the actin depolymerizing factor/cofilin family. Among all members, cofilin‐1 is the predominant isoform. It is located on human chromosome 11q13.
免疫原
The antiserum was produced against synthesized peptide derived from human Cofilin.
Immunogen Range: 61-110
Immunogen Range: 61-110
應用
Anti-Cofilin antibody has been used in western blotting.
生化／生理作用
Cofilin plays an important role in actin filament remodeling that is required in chemotaxis, cell migration and invasion of tumor cells.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Immune-complex level of cofilin-1 in sera is associated with cancer progression and poor prognosis in pancreatic cancer
Satoh M, et al.
Cancer Science, 108, 795-803 (2017)
Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14
Gillett GT, et al.
Annals of Human Genetics, 60 (1996)
Jun-Bum Park et al.
Oncotarget, 5(19), 9382-9395 (2014-09-23)
Malignant gliomas are highly proliferative and invasive neoplasms where total surgical resection is often impossible and effective local radiation therapy difficult. Consequently, there is a need to develop a greater understanding of the molecular events driving invasion and to identify
Irena Audzeyenka et al.
Journal of cellular physiology, 236(6), 4655-4668 (2020-11-28)
Insulin plays a major role in regulating glucose homeostasis in podocytes. Protein kinase G type Iα (PKGIα) plays an important role in regulating glucose uptake in these cells. Rac1 signaling plays an essential role in the reorganization of the actin
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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