SAB4300047

Anti-phospho-PTK2 (pTyr⁸⁶¹) antibody produced in rabbit

affinity isolated antibody

• 别名: Anti-FADK antibody produced in rabbit, Anti-FAK antibody produced in rabbit, Anti-FAK1 antibody produced in rabbit, Anti-PTK2 protein tyrosine kinase 2 antibody produced in rabbit, Anti-pp125FAK antibody produced in rabbit
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: ~125 kDa
• 物種活性: human
• 濃度: 1 mg/mL
• 技術: western blot: 1:500-1:1000
• 同型: IgG
• 免疫原序列: (H-I-YP-Q-P)
• NCBI登錄號: NP_005598.3
• UniProt登錄號: Q05397
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pTyr861)
• 基因資訊: human ... PTK2(5747)

说明

免疫原

Peptide sequence around phosphorylation site of tyrosine 861 (H-I-Y(p)-Q-P), according to the protein PTK2.

特點和優勢

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標靶描述

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable