跳转至内容
Merck

SAB4200576

Sigma-Aldrich

抗-COX2 兔抗

enhanced validation

~1.0 mg/mL, affinity isolated antibody

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~75 kDa

物種活性

human, mouse

加強驗證

recombinant expression
Learn more about Antibody Enhanced Validation

濃度

~1.0 mg/mL

技術

indirect immunofluorescence: 5-10 μg/mL using RAW-264.7 cells stimulated with LPS
western blot: 1.5-3.0 μg/mL using lysates of RAW-264.7 cells stimulated with LPS, and of HEK-293T cells overexpressing human COX2

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... COX2(5743)

正在寻找类似产品? 访问 产品对比指南

一般說明

Cytochrome c oxidase subunit II (COX2) is encoded by the gene mapped to human chromosome 1. The encoded protein is one of the isoforms of COX protein. It is expressed in specific cells such as activated macrophages, monocytes, neutrophils and lymphocytes, in response to inflammatory stimuli such as mitogen, cytokines and growth factors.

免疫原

synthetic peptide corresponding to an internal sequence of human COX2 (GeneID: 5743), conjugated to KLH. The corresponding sequence has high homology to rat COX2 (83% identity) and to mouse COX2 (82% identity).

應用

Anti-COX2 antibody produced in rabbit has been used in immunohistochemical staining.

生化/生理作用

Cyclooxygenase (COX) catalyzes the conversion of arachidonic acid (AA) to prostaglandins (PG). Mutation in the gene is associated with the development of gastric cancer. Elevated expression of the gene has been observed in various chronic and autoimmune diseases.

外觀

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到合适的产品?  

试试我们的产品选型工具.

儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Detection and Clinical Significance of COX-2 Gene SNPs in Gastric Cancer.
Lu X, et al.
Cell Biochemistry and Biophysics, 72(3), 657-660 (2015)
Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors (2012)
Expression of IL-17 and COX2 gene in peripheral blood leukocytes of vitiligo patients.
Esmaeili B, et al.
Iranian Journal of Allergy, Asthma, and Immunology, 10(2), 81-81 (2011)
Immunohistological study of the effect of extravirgin olive oil on aspartame-treated cerebellum of male albino rat
Baky F A F A .
Menoufia Medical Journal, 29(3), 728-728 (2016)
Anna Koumarianou et al.
Anticancer research, 34(9), 4949-4962 (2014-09-10)
Several studies have recently indicated the prognostic or predictive role of several biomarkers in colorectal cancer. We sought to investigate the prognostic value of prostaglandin synthase 2 (PTGS2), cyclooxygenase 2 (COX2), thymidylate synthetase (TYMS), thymidine phosphorylase (TYMP), dihydropyrimidine dehydrogenase (DPYD)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门