SAB4200518

Anti-SLC1A1 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• 别名: Anti-EAAT3, Anti-solute carrier family 1, member 1, EAAC1
• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 共軛: unconjugated
• application: IHC; WB
• 無性繁殖: polyclonal
• 物種活性: mouse, human
• citations: 2
• 技術: immunohistochemistry: 10-20 μg/mL using formalin-fixed paraffin-embedded human small intestine.; western blot: 1.5-3.0 μg/mL using Neuro-2a cell extracts.

属性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen ~70 kDa
• 物種活性: mouse, human
• 加強驗證: recombinant expression; Learn more about Antibody Enhanced Validation
• 濃度: ~1.0 mg/mL
• 技術: immunohistochemistry: 10-20 μg/mL using formalin-fixed paraffin-embedded human small intestine.; western blot: 1.5-3.0 μg/mL using Neuro-2a cell extracts.
• UniProt登錄號: P43005
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SLC1A1(6505) ; mouse ... Slc1a1(20510) ; rat ... Slc1a1(25550)

说明

一般說明

SLC1A1 (also known as EAAC1, EAAT3) is localized at the postsynaptic site of neurons. It is expressed at moderate levels in the adult brain, mainly in the hippocampus, basal ganglia and olfactory bulb and is considered to make a minor contribution to glutamate removal from the synapse.

免疫原

synthetic peptide corresponding to a sequence near the C-terminus of human SLC1A1, conjugated to KLH. The corresponding sequence is identical in mouse and rat SLC1A1.

應用

Anti-SLC1A1 antibody produced in rabbit has been used in immunohistochemistry and immunoblotting.

生化／生理作用

SLC1A1 regulates the developmental effects of glutamate. It is highly regulated by neural activity and intracellular signaling pathways involving mainly PKCa, PI3K, and glial factors, resulting in rapid changes in the trafficking of the transporter and in its membrane location.

外觀

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable