推荐产品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
分子量
92 kDa
物種活性
human
濃度
1 mg/mL
技術
ELISA: suitable
immunohistochemistry: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... TLR4(7099)
一般說明
Toll-like receptor 4 (TLR4) belongs to the interleukin-1 receptor (IL-1R) family. It is highly polymorphic and is located on human chromosome 9q33.1.
免疫原
Antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TLR4.
生化／生理作用
Toll-like receptor 4 (TLR4) acts as the receptor for LPS (lipopolysaccharides ), a gram-negative bacterial cell wall component. Mutations in TLR4 affects mRNA and protein expression in colorectal cancer.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
聯結
The action of this antibody can be blocked using blocking peptide SBP3500765.
外觀
Supplied at 1 mg/mL in PBS with 0.02% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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相關產品
儲存類別代碼
10 - Combustible liquids
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
TLR2 and TLR4 polymorphisms influence mRNA and protein expression in colorectal cancer.
Proenca MA, et al.
World Journal of Gastroenterology, 21(25), 7730-7730 (2015)
TLR4 up-regulation at protein or gene level is pathogenic for lupus-like autoimmune disease.
Liu B, et al.
Journal of Immunology, 177(10), 6880-6888 (2006)
Endotoxin and cytokine regulation of toll-like receptor (TLR) 2 and TLR4 gene expression in murine liver and hepatocytes.
Matsumura T, et al.
Journal of Interferon & Cytokine Research, 20(10), 915-921 (2000)
Xueqin Huang et al.
International immunopharmacology, 22(1), 266-272 (2014-07-17)
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by various immunological abnormalities. Dihydroartemisinin (DHA), a metabolite of artemisinin, has been recently reported to exhibit immunosuppressive properties. The present study aims to determine the effects of DHA on spleen
Jie Dong et al.
The FEBS journal, 281(17), 3803-3815 (2014-07-06)
Interaction between pneumococcal virulence factors and innate immune receptors triggers host responses via specific signaling pathways after infection. By generating a deficient mutant, we show here that, compared with the wild-type parent strain, glycosyl hydrolase 25 relating to invasion protein
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