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Merck
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Key Documents

SAB2500372

Sigma-Aldrich

Anti-EXOC7 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

别名:

Anti-Exo70p, Anti-Exocyst complex component 7, Anti-HGNC:23214

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

goat

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

mouse, rat, human

技術

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... EXOC7(23265)

一般說明

EXOC7 (Exocyst complex component 7) is a major component of a multiprotein, octameric complex, exocyst. It is localized in the active site of active exocytosis.

免疫原

Peptide with sequence C-DNIKNDPDKEYN from the internal region of the protein sequence according to NP_001013861.1; NP_056034.2.

應用

Anti-EXOC7 antibody produced in goat is suitable for immunohistochemistry, indirect ELISA, and western blot analysis.

生化/生理作用

EXOC7 (Exocyst complex component 7) is mainly involved in the exocytosis, a membrane trafficking process of intracellular protein elements such as hormones and neurotransmitters, membrane proteins and lipids to specific domains of the plasma membrane. Exocytosis plays a vital role in the cellular growth, development and cell polarity establishment. During exocytosis, it directly connects with the plasma membrane through its direct interaction with phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)). It has also been reported that the interaction between EXOC7 and PI(4,5)P(2) is highly essential for the docking and fusion of post-Golgi secretory vesicles.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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Shu-Chan Hsu et al.
International review of cytology, 233, 243-265 (2004-03-24)
Exocytosis is an essential membrane traffic event mediating the secretion of intracellular protein contents such as hormones and neurotransmitters as well as the incorporation of membrane proteins and lipids to specific domains of the plasma membrane. As a fundamental cell
Jianglan Liu et al.
Molecular biology of the cell, 18(11), 4483-4492 (2007-09-01)
The exocyst is an evolutionarily conserved octameric protein complex that tethers post-Golgi secretory vesicles at the plasma membrane for exocytosis. To elucidate the mechanism of vesicle tethering, it is important to understand how the exocyst physically associates with the plasma

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