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Merck
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Key Documents

S9991

Sigma-Aldrich

Recombinant SARS-CoV-2 nucleocapsid protein

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.26

形狀

frozen liquid

品質等級

儲存條件

avoid repeated freeze/thaw cycles

技術

ELISA: suitable
lateral flow assay: suitable

儲存溫度

−70°C

一般說明

This Nucleoprotein (nucleocapsid protein) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is expressed in insect cells. The Nucleocapsid protein is not important for determination of neutralizing IgG antibodies. However, the recombinant SARS-CoV-2 Nucleocapsid Protein, S9991 antigen in combination with monoclonal antibodies directed against neutralizing epitopes such as the ACE2 binding domain could be used in a competitive setup for determining neutralizing antibodies. The nucleocapsid protein is quite conserved. Using nucleocapsid protein for acute / early antibodies such as IgA/ IgM should make it possible to detect antibodies directed against the variants of concern in a satisfactory way at an early stage of illness.
For IgM detection, a mixture of nucleocapsid and spike proteins is recommended.

外觀

sab5700595

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1


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