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Merck

S9896

Sigma-Aldrich

皂草素 来源于肥皂草 种子

lyophilized powder

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About This Item

MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.32

生物源

plant seeds (Saponaria officinalis)

品質等級

化驗

10.00-30.00%

形狀

lyophilized powder

成份

Protein, ~20% Lowry

技術

activity assay: suitable

儲存溫度

2-8°C

一般說明

来自皂角种子的皂草素具有一个 N-末端结构域,该结构域为 β-链和一个 C-末端结构域,即 α-螺旋形。由 253 个氨基酸组成,分子量为 28,621 Da。

應用

来自肥皂草种子的皂草素被用来研究它对轮状镰刀霉菌的抗真菌的活动。

生化/生理作用

来自皂角种子的皂草素是一种核糖体失活蛋白。用于制备免疫结合物。已被证明可诱导培养的人淋巴细胞形成微核,从而降低细胞活力,增强细胞凋亡。

包裝

基于蛋白质含量的包装尺寸。

外觀

含葡萄糖和磷酸钠缓冲盐的冻干粉

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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The crystal structure of saporin SO6 from Saponaria officinalis and its interaction with the ribosome.
Savino C
Febs Letters, 470(3), 239-243 (2000)
Elizabeth S Ingham et al.
The Journal of comparative neurology, 516(2), 125-140 (2009-07-04)
In mammals, non-image-forming visual functions, including circadian photoentrainment and the pupillary light reflex, are thought to be mediated by the combination of rods, cones, and the melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs). Although several genetic models have been developed
Fiorenzo Stirpe, Douglas Lappi
Ribosome-inactivating Proteins: Ricin and Related Proteins (2014)
Characterization of the maize b-32 ribosome inactivating protein and its interaction with fungal pathogen development
Chiara Lanzanova
Maydica, 56.1 (2012)
R Iglesias et al.
FEBS letters, 325(3), 291-294 (1993-07-05)
The type 1 ribosome-inactivating protein (RIP) saporin 5 isolated from seeds of Saponaria officinalis L. strongly inhibited translation carried out by Vicia sativa L. purified ribosomes. The toxin multidepurinated V. sativa rRNA, which upon treatment with acid aniline releases several

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