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Merck

S8648

Sigma-Aldrich

Somatotropin (STH) from porcine pituitary

别名:

Growth Hormone

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About This Item

CAS号:
EC號碼:
MDL號碼:
分類程式碼代碼:
51111800
NACRES:
NA.32

無菌

non-sterile

品質等級

形狀

powder

分子量

~22 kDa

包裝

vial of ~50 IU

drug control

Home Office Schedule 4.2

溶解度

ethanolamine: 5 mg/mL (basic buffers, pH 9-10)

UniProt登錄號

運輸包裝

ambient

儲存溫度

2-8°C

基因資訊

pig ... GH(396884)

Amino Acid Sequence

Phe-Pro-Ala-Met-Pro-Leu-Ser-Ser-Leu-Phe-Ala-Asn-Ala-Val-Leu-Arg-Ala-Gln-His-Leu-His-Gln-Leu-Ala-Ala-Asp-Thr-Tyr-Lys-Glu-Phe-Glu-Arg-Ala-Tyr-Ile-Pro-Glu-Gly-Gln-Arg-Tyr-Ser-Ile-Gln-Asn-Ala-Gln-Ala-Ala-Phe-Cys-Phe-Ser-Glu-Thr-Ile-Pro-Ala-Pro-Thr-Gly-Lys-Asp-Glu-Ala-Gln-Gln-Arg-Ser-Asp-Val-Glu-Leu-Leu-Arg-Phe-Ser-Leu-Leu-Leu-Ile-Gln-Ser-Trp-Leu-Gly-Pro-Val-Gln-Phe-Leu-Ser-Arg-Val-Phe-Thr-Asn-Ser-Leu-Val-Phe-Gly-Thr-Ser-Asp-Arg-Val-Tyr-Glu-Lys-Leu-Lys-Asp-Leu-Glu-Glu-Gly-Ile-Gln-Ala-Leu-Met-Arg-Glu-Leu-Glu-Asp-Gly-Ser-Pro-Arg-Ala-Gly-Gln-Ile-Leu-Lys-Gln-Thr-Tyr-Asp-Lys-Phe-Asp-Thr-Asn-Leu-Arg-Ser-Asp-Asp-Ala-Leu-Leu-Lys-Asn-Tyr-Gly-Leu-Leu-Ser-Cys-Phe-Lys-Lys-Asp-Leu-His-Lys-Ala-Glu-Thr-Tyr-Leu-Arg-Val-Met-Lys-Cys-Arg-Arg-Phe-Val-Glu-Ser-Ser-Cys-Ala-Phe

一般說明

Somatotropin or growth hormone is a peptide hormone that is secreted by the anterior pituitary gland. It is essential for growth. The hormone increases muscle mass, reduces fat mass, helps in maintaining normal blood glucose levels and also promotes a balanced lipid profile.

應用

Somatotropin (STH) has been used to study its effects on repressing hepatic H2S production post-transcriptionally. It has also been used as one of the components of a medium to culture primordial follicles.

生化/生理作用

Increases mass of most tissues by increasing cell number rather than cell size, mobilizes fat stores

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Andrzej Bartke et al.
Physiological reviews, 93(2), 571-598 (2013-04-17)
Growth hormone (GH) is a key determinant of postnatal growth and plays an important role in the control of metabolism and body composition. Surprisingly, deficiency in GH signaling delays aging and remarkably extends longevity in laboratory mice. In GH-deficient and
Quantitative expression of antiapoptotic and proapoptotic genes in sheep ovarian follicles grown in vivo or cultured in vitro
V. Praveen
Theriogenology (2015)
[Case report ; a case of Bardet-Biedl syndrome with a pituitary tumor and growth hormone deficiency].
Kumiko Tanaka et al.
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 102(3), 704-707 (2013-06-20)
Busting myths about UK food production.
Georgina Mills
The Veterinary record, 172(13), 323-325 (2013-03-30)
Stephen D McCormick et al.
The Journal of experimental biology, 216(Pt 7), 1142-1151 (2013-03-15)
Freshwater and seawater isoforms of the alpha subunit of Na(+)/K(+)-ATPase (NKA) have previously been identified in gill ionocytes of Atlantic salmon (Salmo salar). In the present study we examine the abundance and cellular localization of these isoforms during the parr-smolt

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