推荐产品
產品線
BioUltra
化驗
≥97% (SDS-PAGE)
形狀
lyophilized powder
比活性
≥4,500 units/mg protein
分子量
32.5 kDa
成份
Protein, ≥95% biuret
相關疾病
arthritis
儲存溫度
−20°C
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相关类别
一般說明
Research area: Cell signaling. Superoxide Dismutase (SOD) is found in allaerobic cells of the animals, plants, and microorganisms. It is a low molecularweight protein that exists as three different forms such as manganese SOD,copper–zinc SOD, and extracellular SOD.
應用
来自牛红细胞的超氧化物歧化酶已用于评估佐剂诱导的关节炎的活性参数的研究中。 来自牛红细胞的超氧化物歧化酶也已用于一项研究中，以简化在10-羧基癸基琼脂糖凝胶上使用电荷控制的疏水色谱法纯化超氧化物歧化酶的过程。
生化／生理作用
牛红细胞来源的超氧化物歧化酶可催化超氧化物自由基歧化为过氧化氢和分子氧。作为一种抗氧化剂，它在保护细胞免受氧自由基毒性作用方面起着至关重要的作用。与一氧化氮(NO)竞争超氧化物阴离子（可与NO反应生成过亚硝酸盐），因此SOD能促进NO的活性。在培养的大鼠卵泡、神经细胞系和转基因小鼠中，SOD也表现出抑制细胞凋亡的作用。
單位定義
在pH 7.8，25℃条件下，3.0mL反应体积中，一个单位可在黄嘌呤氧化酶的偶联系统中抑制细胞色素c的减少达到50％。黄嘌呤氧化酶浓度应每分钟产生 0.025±0.005 的初始 ΔA550 。
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
A García-González et al.
Archives of medical research, 30(2), 132-137 (1999-06-18)
The purpose of this work was to evaluate the effect of superoxide dismutase (SOD) on primary swelling, lipoperoxidation, body thymus, and spleen weight in the adjuvant-induced arthritis (AIA) model in rats. Orally and intraperitoneally administered SOD (100 U/kg) from bovine
Purification of pro- and eukaryotic superoxide dismutases by charge-controlled hydrophobic chromatography
Grunow, M. and W. Schopp
Journal of Chromatography A, 590, 247-253 (1992)
M S Silva et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1104, 262-268 (2018-12-24)
Zinc (Zn) is an element essential to all living organisms and it has an important role as a cofactor of several enzymes. In fish, Zn deficiency has been associated with impaired growth, cataracts, skeletal abnormalities and reduced activity of various
Johannes Björnerås et al.
The FEBS journal, 281(3), 814-824 (2014-03-13)
The molecular determinants for selectivity of ligand binding to membrane receptors are of key importance for the understanding of cellular signalling, as well as for rational therapeutic intervention. In the present study, we target the interaction between the κ opioid
Ashley E Frakes et al.
Neuron, 81(5), 1009-1023 (2014-03-13)
Neuroinflammation is one of the most striking hallmarks of amyotrophic lateral sclerosis (ALS). Nuclear factor-kappa B (NF-κB), a master regulator of inflammation, is upregulated in spinal cords of ALS patients and SOD1-G93A mice. In this study, we show that selective
实验方案
Enzymatic Assay of Superoxide Dismutase
Separation of Superoxide dismutase
Chromatograms
application for HPLC我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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