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Merck

S4019

Sigma-Aldrich

碳酸氢钠

Hybri-Max, powder, suitable for hybridoma, ≥99.5%

别名:

碳酸氢钠, 小苏打

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About This Item

线性分子式:
NaHCO3
CAS号:
分子量:
84.01
Beilstein:
4153970
EC號碼:
MDL號碼:
分類程式碼代碼:
12161702
PubChem物質ID:
NACRES:
NA.75

等級

Hybri-Max

化驗

≥99.5%

形狀

powder

技術

cell culture | hybridoma: suitable

雜質

endotoxin, tested

pH值

8.3 (0.1 molfreshly prepared)

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

溶解度

water: soluble 100 mg/mL

密度

2.16 g/mL at 25 °C (lit.)

SMILES 字串

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI 密鑰

UIIMBOGNXHQVGW-UHFFFAOYSA-M

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應用

碳酸氢钠已作为一种补充剂:
  • 在极限必需培养基(MEM)/冲洗培养基中进行胚胎分离
  • 在TCM 199培养基中收集卵母细胞复合物(COC)并进行体外成熟(IVM)
  • 在IVM培养基中进行COC体外成熟

生化/生理作用

碳酸氢纳在自然状态下以纳石矿的形式存在。它可用于制备许多钠盐以及二氧化碳源。碳酸氢钠可用于制造灭火器和清洁剂。碳酸氢盐在体内pH调节中起着重要作用。碳酸氢钠在生物化学、分子生物学和色谱学中可用作缓冲剂。该Hybri-Max产物用于杂交瘤和细胞研究研究(2.2 mg/ml)。

法律資訊

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Eric A J Hoste et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(3), 747-758 (2009-08-26)
There have been conflicting reports on the use of intravenous administration of sodium bicarbonate for prevention of contrast-induced acute kidney injury (CI-AKI). The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI. This
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to
Joshua C Tremblay et al.
The Journal of physiology, 593(3), 723-737 (2014-11-25)
Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is increased by acute hypoxia during rest by unknown mechanisms. Oral administration of acetazolamide blunts the pulmonary vascular pressure response to acute hypoxia, thus permitting the observation of IPAVA blood flow with minimal
Roberto J Diaz et al.
American journal of physiology. Cell physiology, 306(12), C1191-C1199 (2014-04-25)
We have previously shown that ischemic preconditioning (IPC) protection against necrosis in whole hearts and in both fresh and cultured cardiomyocytes, as well as the improved regulatory volume decrease to hypoosmotic swelling in cardiomyocytes, is abrogated through Cl(-) channel blockade

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