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物種活性
rat
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
輸入
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 μIU/mL
standard curve range: 4.69–300 μIU/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
rat ... Ins1(24505)
一般說明
该试剂盒中提供的抗体对可识别大鼠胰岛素。
應用
仅供研究使用。不可用于诊断操作。
请参考附带的一般ELISA试剂盒操作程序（三明治、竞争性 & 间接ELISA）
请参考附带的一般ELISA试剂盒操作程序（三明治、竞争性 & 间接ELISA）
大鼠Ins1/胰岛素ELSA试剂盒已用于测定血清胰岛素的浓度。
请参阅随附的一般ELISA试剂盒 操作步骤 （夹心、竞争性和间接ELISA）
生化／生理作用
某些物种如小鼠、大鼠和爪蟾具有两个非等位基因胰岛素基因。这些基因是都具功能性的Ins1和Ins2。它们编码在胰腺中分别以1:2比例而生成的胰岛素。这两个基因在小鼠中具有差异表达。Ins1基因定位于端粒区的小鼠19号染色体。胰腺中合成的胰岛素对维持葡萄糖稳态至关重要。Ins-1和Ins-2表达的缺失可导致胰岛素缺乏的小鼠患有糖尿病、酮酸中毒、肝脂肪变性和生长迟缓。
其他說明
本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample 。
请在批号对应的文本框中输入单词 sample 。
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Jingjing Li et al.
Neural plasticity, 2019, 7920540-7920540 (2019-03-27)
We investigated the effects of aerobic exercise on the expression of hippocampal synaptic plasticity-associated proteins in rats with type 2 diabetes and their possible mechanisms. A type 2 diabetes rat model was established with 8 weeks of high-fat diet combined
Jingjing Li et al.
Behavioural brain research, 364, 447-456 (2017-11-09)
Diabetes could negatively affect the structures and functions of the brain, especially could cause the hippocampal dysfunction, however, the potential metabolic mechanism is unclear. The aim of this study was to investigate the changes of glucose metabolism in hippocampus of
Hongtao Tan et al.
Molecular medicine (Cambridge, Mass.), 28(1), 58-58 (2022-05-21)
Glabridin (Glab) is a bioactive component of licorice that can ameliorate diabetes, but its role in diabetic nephropathy (DN) has seldom been reported. Herein, we explored the effect and underlying mechanism of Glab on DN. The bioactive component-target network of
Gregory G Martin et al.
Lipids, 55(4), 309-327 (2020-04-22)
Ad libitum-fed diets high in fat and carbohydrate (especially fructose) induce weight gain, obesity, and nonalcoholic fatty liver disease (NAFLD) in humans and animal models. However, interpretation is complicated since ad libitum feeding of such diets induces hyperphagia and upregulates
Uddipak Rai et al.
Life sciences, 236, 116836-116836 (2019-09-08)
The present experiment was conceptualised to explore the therapeutic response of tetramethylpyrazine (TMP), a major active constituent of Ligusticum chuanxiong, a Chinese traditional medicinal plant, in high-fat diet (HFD)-streptozotocin (STZ)-induced diabetes in rats and to identify the possible mechanism of
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