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Merck

RAB0810

Sigma-Aldrich

Mouse Il18 / Interleukin-18 ELISA Kit

for serum, plasma and cell culture supernatants

别名:

IFN-gamma-inducing factor, IL-18, Interleukin-18 

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About This Item

分類程式碼代碼:
41116158
NACRES:
NA.32

物種活性

mouse

包裝

kit of 96 wells (12 strips x 8 wells)

技術

ELISA: suitable

輸入

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.15 ng/mL
standard curve range: 0.205-50 ng/mL

檢測方法

colorimetric

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

mouse ... Il18(16173)

一般說明

Interleukin-18 (IL-18) belongs to the IL-1 family of cytokines. It is synthesized as an inactive precursor and converted to the active form by caspase-1. IL-18 is involved in the synthesis of interferon-γ (IFN-γ) and IL-13 from T-cells and natural killer (NK) cells. It is a proinflammatory cytokine that aids in the activation of NK cells and T helper 1 cell response. The antibody pair provided in this kit recognizes mouse interleukin 18.
The antibody pair provided in this kit recognizes Mouse Interleukin 18.

應用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Mouse Il18 / Interleukin-18 ELISA Kit has been used to detect interleukin-18 in serum samples.

其他說明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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产品编号
说明
化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)化学品安全说明书

  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形圖

Corrosion

訊號詞

Warning

危險聲明

防範說明

危險分類

Met. Corr. 1

儲存類別代碼

8A - Combustible corrosive hazardous materials

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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T Yoshimoto et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(24), 13962-13966 (1999-11-26)
IL-18 is a proinflammatory cytokine that plays an important role in natural killer cell activation and T helper 1 (Th1) cell responses. Mast cells and basophils are major inducers and effectors of allergic inflammation. Here we show that basophils and
Charles A Dinarello et al.
Frontiers in immunology, 4, 289-289 (2013-10-12)
Interleukin-18 (IL-18) is a member of the IL-1 family of cytokines. Similar to IL-1β, IL-18 is synthesized as an inactive precursor requiring processing by caspase-1 into an active cytokine but unlike IL-1β, the IL-18 precursor is constitutively present in nearly
Benjamin Uzan et al.
EMBO molecular medicine, 6(6), 821-834 (2014-04-30)
Development of novel therapies is critical for T-cell acute leukaemia (T-ALL). Here, we investigated the effect of inhibiting the MAPK/MEK/ERK pathway on T-ALL cell growth. Unexpectedly, MEK inhibitors (MEKi) enhanced growth of 70% of human T-ALL cell samples cultured on
Zufeng Ding et al.
Biochemical and biophysical research communications, 451(4), 637-643 (2014-08-19)
Lectin-like oxidized low-density lipoprotein scavenger receptor-1 (LOX-1) is known to be involved in many pathophysiological events, such as inflammation. To clarify the role of LOX-1 in mtDNA damage and NLRP3 inflammasome activation, we studied wild-type (WT) and LOX-1 knockout (KO)
Jin-Mei Chen et al.
Cytokine, 119, 113-118 (2019-03-25)
Recent studies have provided overwhelming evidence of the involvement of microglia-related molecular networks in the pathogenesis of Alzheimer's diseases (AD). The potential involvement of pro-inflammatory cytokines interleukin (IL)-18, IL-23 and IL-17 on amyloid (Aβ) clearance is still unclear. In this

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