RAB0780

小鼠Tyro3 /酪氨酸蛋白激酶受体TYRO3 ELISA试剂盒

• 分類程式碼代碼: 41116158
• NACRES: NA.32

属性

• 物種活性: mouse
• 包裝: kit of 96 wells (12 strips x 8 wells)
• 技術: ELISA: suitable
• 輸入: sample type cell culture supernatant(s); sample type serum; sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 0.4 ng/mL; standard curve range: 0.416-100 ng/mL
• 檢測方法: colorimetric
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: mouse ... Tyro3(22174)

说明

一般說明

The antibody pair provided in this kit recognizes mouse Tyro3.

應用

请参考Protocol了解详情。

生化／生理作用

Tyrosine-protein kinase receptor (TYRO3) is a transmembrane tyrosine kinase receptor. It plays a significant role in the brain development during embryogenesis. It plays an important role in apoptotic cell clearance. In hepatocellular carcinoma, it is associated with tumor growth, aggressiveness and liver dysfunction. Mutations in the TYRO3 gene intronic regions are linked with asthma. TYRO3 is also a suppressor of type 2 immunity. As part of the TAM (TYRO3, AXL and MER receptors) family, it is activated by PROS1 (protein S) and GAS6 (growth arrest-specific gene 6). Changes in the expression of TYRO3 are linked with the proliferation and survival of cancer cells. Absence of TYRO3 in mice results in neurological disorders.

试剂盒组分也可单独购买

• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABWASH4 20X Wash Buffer (Item B)

安全信息

• 象形圖: GHS05
• 訊號詞: Warning
• 危險聲明: H290
• 防範說明: P234 - P390
• 危險分類: Met. Corr. 1
• 儲存類別代碼: 8A - Combustible corrosive hazardous materials
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable