R5258

核黄素结合蛋白 来源于鸡蛋白

lyophilized powder

• 别名: Binding Protein, Chicken Egg White Protein, Riboflavin Protein
• 分類程式碼代碼: 12352202
• NACRES: NA.26

属性

• 生物源: chicken egg white
• 品質等級: 200
• 形狀: lyophilized powder
• 濃度: ≥50% protein (biuret)
• UniProt登錄號: P02752
• 儲存溫度: −20°C
• 基因資訊: chicken ... RBP(396449)

说明

一般說明

Riboflavin Binding Protein (RBP) comprises of 19 cysteines and corresponds to a molecular weight of 30 kDa. Egg white RBP is produced in the oviduct cells. Chicken egg white RBP contains an N-terminal ligand binding domain and a C-terminal phosphorylated motif.

Riboflavin binding protein (RBP) transports riboflavin through the bloodstream of the laying hen into the eggs, where the vitamin is essential for embryonic growth and development. RBP consists of a single polypeptide chain containing 9 disulfide bonds. It is a glycoprotein containing ~14% carbohydrate, with sugar moieties including galactose, mannose and glucosamine, and is phosphorylated.

應用

Riboflavin Binding Protein from chicken egg white may be used in fluorescence quenching experiments.

生化／生理作用

Riboflavin Binding Protein (RBP) is crucial for normal embryo development. RBP interacts with riboflavin and its analogs. The RBP-riboflavin complex is stabilized by interaction between the isoalloxazyne ring of riboflavin and the tyrosine 75 and tryptophan 156 of residues of RBP. RBP elicits sweet supressing functionality and may interact with the sweet taste receptor.

Riboflavin binding protein binds to flavokinase and regulates its activity.

準備報告

Supplied as the riboflavin-depleted apo-form.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)