R3530

Rifabutin

>98% (HPLC), powder, antibiotic

• 别名: Ansamycin, Ansatipine (Farmitalia), LM-427, Mycobutin (Farmitalia)
• 经验公式（希尔记法）: C₄₆H₆₂N₄O₁₁
• CAS号: 72559-06-9
• 分子量: 847.00
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 产品名称: Rifabutin, >98% (HPLC), powder
• 化驗: >98% (HPLC)
• 形狀: powder
• 儲存條件: protect from light
• 溶解度: DMSO: >5 mg/mL
• 抗生素活性譜: neoplastics
• 作用方式: enzyme | inhibits
• 起源: Johnson & Johnson
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• SMILES 字串: [N+H]1(CCC2(NC3=C4NC(=O)\C(=C/C=C/[C@@H]([C@@H]([C@H]([C@H]([C@H]([C@@H]([C@@H]([C@H](\C=C\O[C@]5(Oc6c(c(c(c(c6C)[O-])C4=O)C3=N2)C5=O)C)OC)C)OC(=O)C)C)O)C)O)C)\C)CC1)CC(C)C
• InChI: 1S/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12+,20-15+,24-14-/t23-,25+,26+,27+,30-,37-,38+,41+,45-/m0/s1
• InChI 密鑰: ATEBXHFBFRCZMA-VXTBVIBXSA-N

说明

生化／生理作用

Rifabutin is an antibiotic; antitumor.

Rifabutin is an antibiotic; antitumor. Rifabutin interferes with HSP-90 molecular chaperone, enhances ubiquitination and protein degradation, and inactivates bacterial RNA polymerase.

特點和優勢

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)