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Merck

Q2128

Sigma-Aldrich

使君子氨酸

powder

别名:

β-(3,5-二氧代-1,2,4-氧杂重氮烷-2-基)-L-丙氨酸

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About This Item

经验公式(希尔记法):
C5H7N3O5
CAS号:
分子量:
189.13
Beilstein:
1078734
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.32

形狀

powder

品質等級

顏色

white to off-white

溶解度

ethanol: <0.17 mg/mL
H2O: 0.5 mg/mL
0.1 M HCl: 1.4 mg/mL
1 M NH4OH: 20 mg/mL
organic solvents: insoluble

儲存溫度

2-8°C

SMILES 字串

N[C@@H](CN1OC(=O)NC1=O)C(O)=O

InChI

1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1

InChI 密鑰

ASNFTDCKZKHJSW-REOHCLBHSA-N

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一般說明

Quisqualate/ Quisqualic acid is obtained from the fruits and seeds of Quisqualis chinensis. It is an agonist at two subsets of excitatory amino acid receptors metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores and, ionotropic receptors that directly control membrane channels. L-quisqualic acid is an agonist of the neurotransmitter L-glutamate.

應用

Quisqualic acid has also been used as a group I metabotropic receptor agonist in neurons.
Quisqualic acid has been used to test ligand-gated receptors in spiral ganglion neurons.

生化/生理作用

Active enantiomer of quisqualic acid; excitatory amino acid at glutamate receptors.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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The Journal of neuroscience : the official journal of the Society for Neuroscience, 29(29), 9281-9291 (2009-07-25)
Little is known about the generation of slow rhythms in brain neuronal circuits. Nevertheless, a few studies, both from reconstituted systems and from hippocampal slices, indicate that activation of metabotropic glutamate receptors (mGluRs) could generate such rhythms. Here we show
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