推荐产品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
predicted mol wt 32 kDa
物種活性
mouse, human
技術
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... PDCD1(5133)
一般說明
PD-1（程序性死亡受体-1）是一种免疫抑制分子，也称为PDCD1（程序性细胞死亡蛋白1）。它位于染色体2q37.3上。是免疫球蛋白受体超家族的成员之一。
免疫原
由人PD-1羧基末端附近的16个氨基酸组成的肽。
生化／生理作用
PD-1（程序性死亡1，programmed death-1）基因对系统性红斑狼疮（SLE）敏感。PD-1的多态性可能参与EOG（上皮性卵巢癌）的生长。它可作为T细胞的负调节剂。它还导致肿瘤细胞介导的免疫逃逸。
聯結
可以使用阻断肽 SBP4065阻断该抗体的作用。
外觀
溶剂为含有0.02％叠氮化钠的磷酸盐缓冲盐水
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
A new haplotype of PDCD1 is associated with rheumatoid arthritis in Hong Kong Chinese
Kong EK, et al.
Arthritis and Rheumatism, 52(4), 1058-1062 (2005)
The effect of polymorphisms in PD-1 gene on the risk of epithelial ovarian cancer and patients' outcomes
Li Y, et al.
Gynecologic Oncology, 144(1), 140-145 (2017)
Gang Chen et al.
Nature neuroscience, 20(7), 917-926 (2017-05-23)
Programmed cell death ligand-1 (PD-L1) is typically produced by cancer cells and suppresses immunity through the receptor PD-1 expressed on T cells. However, the role of PD-L1 and PD-1 in regulating pain and neuronal function is unclear. Here we report
Christopher H Cogbill et al.
American journal of clinical pathology, 142(1), 88-98 (2014-06-14)
CD279 expression is used to help identify angioimmunoblastic T-cell lymphoma (AITL) or other T-cell lymphomas of T-follicular helper (TFH) cell origin; however, its utility in assessing lymphoid infiltrates in the bone marrow (BM) is not well established. Immunohistochemistry for CD279
Zhi-Chun Ding et al.
Cancer research, 74(13), 3441-3453 (2014-05-02)
In recent years, immune-based therapies have become an increasingly attractive treatment option for patients with cancer. Cancer immunotherapy is often used in combination with conventional chemotherapy for synergistic effects. The alkylating agent cyclophosphamide (CTX) has been included in various chemoimmunotherapy
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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