PRS2501

Anti-CIKS antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 别名: Anti-TRAF3 Interacting protein 2
• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 無性繁殖: polyclonal
• application: ELISA (i); IF; IHC; WB
• 物種活性: human
• 技術: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• citations: 4

属性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: predicted mol wt 63 kDa
• 物種活性: human
• 技術: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt登錄號: O43734
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... TRAF3IP2(10758)

说明

一般說明

CIKS (connection to IKK (IκB kinase) and SAPK (stress-activated protein kinase) /JNK (jun kinase)) is a cytoplasmic protein, that exists in the nucleus. It is also termed as Act1(NF-κB activator 1) and TRAF3IP2 (TRAF3 interacting protein 2). It is located on chromosome 6q21.

免疫原

a synthetic peptide corresponding to amino acids 2-15 of human CIKS.

生化／生理作用

CIKS (connection to IKK (IκB kinase) and SAPK (stress-activated protein kinase) /JNK (jun kinase)) is susceptible to various diseases like psoriasis and psoriatic arthritis. It is responsible for the cardiomyocyte growth, fibroblast migration and proliferation, promoted by aldosterone. It participates in the signaling function of IL-17 (interleukin) cytokine family. It can act as a transcriptional enhancer due to its presence in the nuclear compartment of airway epithelial cells.

聯結

The action of this antibody can be blocked using blocking peptide SBP2501.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable