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Key Documents

PLA0096

Sigma-Aldrich

Rabbit anti-p300 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

别名:

300kD, E1A-associated protein p300, E1A-binding protein, KAT3B, RSTS2, histone acetyltransferase p300, p300, p300 HAT

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

等級

Powered by Bethyl Laboratories, Inc.

物種活性

human

技術

ChIP: 10 μg
immunohistochemistry: 1:1,000- 1:5,000
immunoprecipitation (IP): 1-5 μg/mg
western blot: 1:2,000-1:10,000

登錄號

NP_001420.2

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

rabbit ... p300(2033)

相关类别

免疫原

The epitope recognized by PLA0096 maps to a region between residues 950 and 1000 of human E1A-associated protein p300 using the numbering given in entry NP_001420.2 (GeneID 2033).

外觀

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

其他說明

By sequence similarity p300 is related to CBP (CREB-binding protein) and functions as a histone acetyltransferase that can regulate transcription by influencing chromatin organization. P300 has been demonstrated to bind to phosphorylated CREB to mediate cAMP-gene regulation. P300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha).

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Robin P Smith et al.
PLoS genetics, 10(10), e1004648-e1004648 (2014-10-03)
Inter-individual variation in gene regulatory elements is hypothesized to play a causative role in adverse drug reactions and reduced drug activity. However, relatively little is known about the location and function of drug-dependent elements. To uncover drug-associated elements in a

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