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Merck

P5874

Sigma-Aldrich

PTACH

≥98% (HPLC), solid

别名:

Cpd 51, S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl] thioisobutyrate

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About This Item

经验公式(希尔记法):
C20H26N2O2S2
分子量:
390.56
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

solid

溶解度

DMSO: 26 mg/mL

儲存溫度

2-8°C

SMILES 字串

CC(C)C(=O)SCCCCCCC(=O)Nc1nc(cs1)-c2ccccc2

InChI

1S/C20H26N2O2S2/c1-15(2)19(24)25-13-9-4-3-8-12-18(23)22-20-21-17(14-26-20)16-10-6-5-7-11-16/h5-7,10-11,14-15H,3-4,8-9,12-13H2,1-2H3,(H,21,22,23)

InChI 密鑰

MDYDGUOQFUQOGE-UHFFFAOYSA-N

生化/生理作用

HDAC inhibitor; more potent than the majority of HDAC inhibitors except for SAHA (gold standard).

特點和優勢

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Minghui Wang et al.
Neuron, 109(2), 257-272 (2020-11-26)
To identify the molecular mechanisms and novel therapeutic targets of late-onset Alzheimer's Disease (LOAD), we performed an integrative network analysis of multi-omics profiling of four cortical areas across 364 donors with varying cognitive and neuropathological phenotypes. Our analyses revealed thousands

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Epigenetic modifications are thought to occur through two key interconnected processes—DNA methylation and the covalent modification of histones.

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