推荐产品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
lyophilized powder
物種活性
mouse, rat, human
技術
immunohistochemistry: suitable
western blot: 1:200-1:500
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... NGFR(4804)
mouse ... Ngfr(18053)
rat ... Ngfr(24596)
特異性
pro-BDNF、pro-NT-3 或成熟的 NGF 不会发生交叉反应。
免疫原
对应于大鼠 NGF(前体)84-104 氨基酸残基的肽。该序列在小鼠中相同,在人中 16/21 个残基相同。
外觀
采用 pH 7.4 的磷酸盐缓冲盐水、1%BSA 和0.1% 叠氮化钠冻干而成
準備報告
用 0.2 mL 去离子水复溶冻干瓶。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Dermal - Aquatic Chronic 3
儲存類別代碼
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Comparison of nerve growth factor receptor binding models using heterodimeric muteins
Journal of Neuroscience Research, doi: 10-doi: 10 (2012)
Molecular and cellular neurosciences, 18(2), 210-220 (2001-08-25)
Nerve growth factor (NGF) is important for regulation, differentiation, and survival of peripheral and central nervous system neurons, including basal forebrain cholinergic neurons (BFCN) which degenerate in Alzheimer's disease (AD). Mature NGF protein is processed from a larger precursor, proNGF.
Death of injured neurons caused by the precursor of nerve growth factor.
Proceedings of the National Academy of Sciences of the United States of America, 101(16), 5703-5704 (2004-04-14)
Neuron, 39(5), 735-738 (2003-09-02)
Neurotrophins are synthesized first as precursors, followed by maturation through proteolytic removal of the "pro" region. Since pro- and mature neurotrophins elicit opposite functional effects by differential interactions with Trks and p75 receptors, extracellular cleavage represents a new way to
Drug design, development and therapy, 13, 2513-2532 (2019-08-24)
Nowadays, the drug delivery system is important in the treatment of diseases. A polymeric nanoparticle modified by oleic acid (NPMO) as a Thymol (Thy) drug release system was synthesized from Thymbra spicata and its neurotrophic and angiogenic effects on rat's
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