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P3657

Sigma-Aldrich

吡哆醛5'-磷酸盐 水合物

powder, BioReagent, suitable for cell culture

别名:

3-羟基-2-甲基-5-([磷酰氧基]甲基）-4-吡啶甲醛, PLP, 吡哆醛5-磷酸, 辅脱羧酶

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About This Item

经验公式（希尔记法）:
C8H10NO6P · xH2O
CAS号:
853645-22-4
分子量:
247.14 (anhydrous basis)
Beilstein:
234749
EC號碼:
200-208-3
MDL號碼:
MFCD00006333
分類程式碼代碼:
12352205
PubChem物質ID:
24898438
NACRES:
NA.75

產品線

BioReagent

品質等級

200

化驗

≥98%

形狀

powder

分子量

Mw 247.14 g/mol

技術

cell culture | mammalian: suitable

顏色

off-white to yellow-brown

mp

140-143 °C

溶解度

1 M HCl: soluble 50 mg/mL, clear, colorless to light yellow-green

儲存溫度

−20°C

SMILES 字串

CC1=NC=C(COP(O)(O)=O)C(C([H])=O)=C1O

InChI

1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)

InChI 密鑰

NGVDGCNFYWLIFO-UHFFFAOYSA-N

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相关类别

一般說明

磷酸吡哆醛（PLP，Pyridoxal-5'-磷酸盐，P5P）是一些酶的辅基。它是维生素 B6 的活性形式，由吡哆醛、吡哆胺和吡哆醇三种天然有机化合物组成。PLP 在所有的转氨反应中，以及在一些氨基酸的脱羧和脱氨反应中都起辅酶的作用。

應用


  • 血液透析膜的分层表面结构，基于5′-磷酸吡哆醛的多功能作用去除同型半胱氨酸。：讨论了使用吡哆醛5′-磷酸的先进血液透析膜的发展，强调了其在降低同型半胱氨酸水平方面的作用，可能有助于改善透析患者的预后（Jiang P et al., 2020）。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCK7246
SLCD6819
SLBZ7499
SLBP7347V
SLBM9225V

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Ivone Carvalho et al.
Bioorganic & medicinal chemistry, 18(7), 2412-2427 (2010-03-26)
Trypanosoma cruzi trans-sialidase (TcTS) plays a key role in the recognition and invasion of host cells and in enabling the parasite to escape the human immune response. To explore this potential drug target, we have synthesized a small library of
Jennifer H Richens et al.
Biology open, 4(8), 1052-1061 (2015-07-15)
Centrosomes comprise a pair of centrioles surrounded by a matrix of pericentriolar material (PCM). In vertebrate cells, Pericentrin plays an important part in mitotic PCM assembly, but the Drosophila Pericentrin-like protein (PLP) appears to have a more minor role in
Trina Das et al.
The Journal of general virology, 96(Pt 2), 294-310 (2014-10-30)
Chikungunya virus (CHIKV) has recently affected millions of people in the Indian Ocean, with rare cases of encephalopathy and encephalitis occurring in neonates. In the study described herein, the capacity of mouse brain cells to control infection through innate immune
Bogdan F G Popescu et al.
Neurology, 84(2), 148-158 (2014-12-17)
To assess, in a surgical biopsy cohort of active demyelinating lesions, the diagnostic utility of aquaporin-4 (AQP4) immunohistochemistry in identifying neuromyelitis optica (NMO) or NMO spectrum disorder (NMOSD) and describe pathologic features that should prompt AQP4 immunohistochemical analysis and AQP4-immunoglobulin
Alexandros K Kanellopoulos et al.
Cell, 180(6), 1178-1197 (2020-03-24)
Social impairment is frequently associated with mitochondrial dysfunction and altered neurotransmission. Although mitochondrial function is crucial for brain homeostasis, it remains unknown whether mitochondrial disruption contributes to social behavioral deficits. Here, we show that Drosophila mutants in the homolog of
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